What causes a perforated stomach (gastric perforation)?

Overview: What Is Gastric Perforation?

Gastric perforation is one of the most common surgical emergencies in abdominal surgery. It typically presents with sudden, sharp, knife-like pain in the upper abdomen, which quickly spreads throughout the entire abdomen as diffuse peritonitis develops.

The primary causes include:

  • Peptic ulcers (most commonly gastric or duodenal ulcers)
  • Stress-induced ulcers

As an ulcer deepens over time, it erodes through the muscular and serosal layers of the stomach wall until it finally penetrates the stomach wall entirely, causing a perforation.

Other contributing factors may include:

  • Gastric cancer
  • Abdominal trauma
  • Heavy smoking or alcohol abuse
  • Overeating
  • Long-term use of corticosteroids

Treatment Recommendations

Management depends on the severity and timing of the perforation:

  • Small perforations without peritonitis (e.g., those occurring while fasting) may be treated conservatively:
    • Strict NPO (nothing by mouth)
    • Nasogastric tube insertion to decompress and drain gastric contents
    • Intravenous fluids to correct dehydration and electrolyte imbalances
    • Antibiotics to prevent secondary intra-abdominal infection (e.g., cefoperazone in normal saline, given IV)
    • Potassium chloride supplementation as needed
  • Perforations after a meal are medical emergencies:
    When stomach contents leak into the peritoneal cavity, they trigger chemical peritonitis, followed rapidly by bacterial peritonitis and potentially septic shock.
    Immediate surgical intervention is required—delay can be life-threatening.

Dietary & Lifestyle Advice for Prevention

To reduce the risk of gastric perforation and support overall stomach health:

  • Avoid pickled, salty, or highly processed foods (e.g., pickled vegetables, salted duck eggs).
  • Limit spicy, raw, or irritating foods such as chili peppers, raw garlic, onions, and strong seasonings.
  • Eat regular, moderate-sized mealschew thoroughly and eat slowly.
  • Prefer small, frequent meals over large ones.
  • Choose soft, easily digestible foods; avoid coarse or rough-textured items.

Recommended foods:

  • Fresh fruits and vegetables rich in vitamin C (e.g., apples, bananas, oranges, bok choy, spinach, rapeseed greens)
  • Moderate amounts of lean protein: skinless poultry, eggs, low-fat milk, and lean meats

Lifestyle tips:

  • Keep your abdomen warm—cold exposure can impair gastric function.
  • Never binge eat. After a large meal, take a gentle walk instead of bending over, squatting, or engaging in strenuous activity, as these actions increase intra-abdominal pressure and may trigger perforation in vulnerable individuals.

Prevention is key: Managing ulcers early, avoiding risk factors, and maintaining healthy eating habits significantly lower the chance of this life-threatening condition.